Patrick Sawyer, a consultant for the Liberian finance ministry aged in his 40s, collapsed on arrival at Lagos airport on July 20. He was put in isolation at the First Consultants Hospital in Obalende, one of the most crowded parts of a city that is home to 21 million people, and died on Friday.
"The private hospital was demobilized (evacuated) and the primary source of infection eliminated. The decontamination process in all the affected areas has commenced," Lagos state health commissioner Jide Idris told a news conference.
Some hospital staff who were in close contact with the victim have been isolated. The hospital will be shut for a week and all staff closely monitored, Idris added.
Authorities are monitoring a total of 59 people who were in contact with Sawyer, including airport contacts, the Lagos state health ministry said. But the airline he flew in with has yet to provide a passenger list for the flights he used, it added.
Ebola has killed 672 people across Guinea, Liberia and Sierra Leone since it was first diagnosed in February.
The fatality rate of the current outbreak is around 60 percent although the disease can kill up to 90 percent of those who catch it. Highly contagious, its symptoms include vomiting, diarrhea and internal and external bleeding.
Derek Gatherer, a virologist at Britain's University of Lancaster, said anyone on the plane near Sawyer could be in "pretty serious danger", but that relatively wealthy Nigeria was better placed to tackle the outbreak than poorer neighbors.
"Nigerians have deep pockets and they can do as much as any Western country could do if they have the motivation and organization to get it done," he said.
Nigeria's largest air carrier Arik Air has suspended flights to Liberia and Sierra Leone because of the risk of Ebola, Arik spokesman Ola Adebanji said in emailed response on Monday.
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